Analysis of Heart Rate Variability After a Physical Exercise Session

Not Applicable

Completed

• Conditions: Hypertension
• Interventions: Other: Aerobic Exercise. 1 session of acute exercise; Other: Resistance Exercise. 1 session of acute exercise; Other: no exercise

• Registration Number: NCT05798975
• Lead Sponsor: Instituto de Cardiologia do Rio Grande do Sul

Brief Summary

Systemic arterial hypertension (SAH) is a multifactorial clinical condition, characterized by sustained elevation of blood pressure levels, contributing to 50% of deaths from cardiovascular disease. The Autonomic Nervous System (ANS) plays a fundamental role in the regulation of Blood Pressure (BP) and is closely associated with Heart Rate (HR). HR changes are called Heart Rate Variability (HRV). In individuals with SAH, HRV indices are reduced compared to normotensive individuals, showing changes in autonomic modulation, thus increasing the risk for cardiovascular events. The objective of this study will be to analyze the Heart Rate Variability in individuals with controlled SAH after a session of aerobic (EA) or resistance (RE) physical exercise.

Detailed Description

Controlled hypertensive individuals aged between 30 and 59 years will be selected, for convenience, who use the services of the Instituto de Cardiologia do Rio Grande do Sul. Volunteers will be randomly assigned to an EA session (40 minutes on cycle ergometer, 60% of heart rate reserve) or RE (2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM) or control group without exercise. HRV data will be collected by ECG (Wincardio USB - Version 11.1.0.0, MICROMED Biotecnologia Ltda, Brasília - DF - Brazil) during 10 minutes before the exercise session, 10 minutes after the exercise session, 1h and 2h post-session . It is expected to estimate results that may demonstrate clarifications about the impact of a physical exercise session on HRV in controlled hypertensive individuals.

Study Timeline

• Study Start: 2022-04-01
• Study First Submitted: 2023-02-10
• Study First Submitted QC: 2023-03-22
• Study First Posted: 2023-04-05
• Primary Completion: 2024-10-01
• Study Completion: 2024-11-30
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-12
• Last Update Posted: 2025-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Controlled Systemic Alterial Hypertension

Exclusion Criteria

• Diabetes mellitus;
• heart failure;
• coronary artery disease;
• chronic renal failure;
• body mass index (BMI) ≥ 35 kg/m2;
• smokers;
• individuals with injuries to the upper and lower limbs that make the exercise protocol impossible;
• not using antihypertensive medication and using beta-blocker and/or alpha-blocker medication.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic Physical Exercise	no exercise	Cycle ergometer exercise
Resistance Physical Exercise	Aerobic Exercise. 1 session of acute exercise	Exercise with weights
Resistance Physical Exercise	no exercise	Exercise with weights
Aerobic Physical Exercise	Resistance Exercise. 1 session of acute exercise	Cycle ergometer exercise

Primary Outcome Measures

Name	Time	Method
Heart Rate Variability.	4 hours	Analysis of heart rate variability with Wincardio Digital ECG.

Trial Locations

Locations (1)

Diego Silveira da Silva; 🇧🇷 Porto Alegre, RS, Brazil