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临床试验/NL-OMON55881
NL-OMON55881已完成不适用

Validation of bi-dimensional (2D) and three-dimensional (3D) Fourier Decomposition (FD) as Magnetic Resonance Imaging (MRI) technique to assess lung ventilation and perfusion compared to computed tomography (CT), Hyperpolarised gases (HP-MRI) and Contrast-Enhanced MRI (CE-MRI) - VIPS MRI

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 19 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
19

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
2 至 99(—)

入选标准

  • CF patients
  • Diagnosed with CF with sweat and genetic testing
  • Age between 10-18 years
  • Scheduled for biennial CT scan
  • Willing and capable to perform spirometer controlled chest MRI
  • Informed consent
  • Healthy Volunteers
  • Age 10-18 years
  • Willing and capable to perform spirometer controlled chest MRI
  • Informed consent
  • Healthy volunteers (MRI standardization)
  • Age 18 years and older
  • Willing and capable to perform chest MRI
  • Informed consent

排除标准

  • MRI contraindication (i.e. cardiac pacemaker, metallic implant, hearing aids,
  • Claustrophobic
  • Pregnancy
  • Not willing or unable to perform MRI
  • CF Patients
  • Recent (< 1 month) RTE with use of i.v. antibiotics
  • Chronic oxygen therapy
  • Any other severe comorbidities that could limit imaging
  • Healthy volunteers
  • Recent (< 1 month) history of lung disease (i.e. pneumonia)
  • Known history of chronic lung disease (i.e. asthma)
  • Known history of congenital lung disease (i.e. bronchopulmonary dysplasia,
  • tracheomalacia)

研究者

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