Factors that influence womens utilization of prenatal screening for Downs syndrome. Optimizing decision making and refining current and future screening policies by studying differences in uptake rates, between three European countries*

Completed

Conditions: Down syndrome
trisomy 21
10083624
10026908

Registration Number: NL-OMON38077

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 112

Inclusion Criteria

Pregnant women:
- Participants should be older than 18, and confirmed pregnancy
- Good understanding of Dutch language
- Gestational age <10 weeks, 11-13 weeks and 14-20 weeks
- Singleton pregnancy
-

Exclusion Criteria

- Non pregnant women
- Pregnant women age < 18
- Former history of fetal anomalies
• Current pregnancy with fetal anomalies or maternal complications
• Pregnancy perceived by assisted reproductive technology

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The approach of the study will be a mixed method, also called a sequential<br /><br>exploratory approach, consisting of a review, desk research, completed with<br /><br>stakeholders interviews in the three countries, qualitative focus group<br /><br>discussions and semi-quantitative large-scale questionnaires.<br /><br>In this study, we are interested in participant*s reasons to decline or accept<br /><br>DSS. First, we want to determine which factors correlate with declining or<br /><br>accepting the test. As these data consider feelings, perceptions and<br /><br>interpretations of different levels, a qualitative approach is most suitable to<br /><br>provide this information. After we have determined discriminating factors of<br /><br>influence, we will perform large-scale questionnaires to determine if these<br /><br>findings are representative for large groups. Therefore a semi-quantitative<br /><br>approach is most applicable.</p><br>

Secondary Outcome Measures