Comparison of Spine Posture, Trunk Position Sense and Gait Characteristics Among Different Sub-types of Axial Spondyloarthritis Patients and Healthy Controls
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Non-radiographic Axial Spondyloarthritis
- Sponsor
- Necmettin Erbakan University
- Enrollment
- 75
- Locations
- 1
- Primary Endpoint
- Spine posture
- Last Updated
- 4 years ago
Overview
Brief Summary
Axial Spondyloarthritis (Ax-SpA) are chronic systemic inflammatory rheumatological diseases characterized by axial skeletal involvement and enthesitis. Sacroiliitis is the most prominent sign of the disease. The International Society for the Evaluation of Spondyloarthritis created a new classification for Ax-SpA in 2009. According to this classification, Ax-SpA; It is divided into two groups as ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA).
With the emergence of the term nr-axSpA, studies have begun to compare AS and nr-axSpA in terms of genetic, epidemiological and clinical features, treatment needs and response to treatment.However, more studies are needed to better understand the clinical features and symptoms of nr-axSpA patients.
The aim of this study was to determine the clinical features of patients with nr-axSpA and AS; To evaluate spine posture, trunk position sense and gait parameters, and also to compare these results with healthy individuals.
Detailed Description
There are no studies comparing spine posture, trunk position sense and gait parameters in patients with nr-axSpA and AS. It is important to determine the changes that occur in nr-axSpA patients in the early period. At the same time, taking the necessary precautions and following these patients with the rehabilitation process can ensure that the radiographic development is delayed or not at all in the future. Hypotheses: H1: Trunk position sense is different from each other in individuals with Nr-axSpA and AS. H2: Spatio-temporal features of gait are different in individuals with Nr-axSpA and AS. H3: Plantar pressure distribution is different in individuals with Nr-axSpA and AS. The Location of the Research: The research is carried out in Konya Necmettin Erbakan University Meram Faculty of Medicine, Rheumatology Department. After obtaining the permission of the ethics committee, official permission was obtained from Necmettin Erbakan University Meram Medical Faculty Hospital Chief Physician to conduct the study.
Investigators
YASEMİN AKKUBAK
Research Assistant
Necmettin Erbakan University
Eligibility Criteria
Inclusion Criteria
- •For AS and nr-axSpA;
- •Diagnosed with AS and nr-axSpA by a rheumatologist according to ASAS criteria,
- •Diagnosed with AS and nr-axSpA at least two years ago,
- •Volunteer to participate in the study,
- •Individuals between the ages of 18-65 will be included in the study.
- •For Healthy volunteers;
- •Volunteer to participate in the study,
- •Individuals between the ages of 18-65 will be included in the study.
Exclusion Criteria
- •For AS and nr-axSpA;
- •Having orthopedic problems in the lower extremity,
- •Locomotor disorders (fractures and prostheses) and / or osteoporosis,
- •Having a history of lower extremity and spine surgery,
- •Having neurological and cognitive problems,
- •Having vision and hearing problems,
- •Regular exercise,
- •Individuals with kyphosis above 50 degrees will be excluded from the study.
- •For Healthy volunteers;
- •Having any musculoskeletal, neurological and rheumatological diseases,
Outcomes
Primary Outcomes
Spine posture
Time Frame: 6 months
Thoracic and lumbar curvature tests will be performed with a digital inclinometer (Acumar®, Dual Digital Inclinometer, Lafayette Instrument Company, IN, USA). For throcic curvature, the 7th cervical vertebra, the most prominent spinous process, and the sacrum will be used as reference points to palpate the spinal processes of T1-T2 and T12-L1, respectively. The feet of the inclinometers will be placed as simultaneously as possible over T1-T2 and T12-L1. The angle on the digital display of the inclinometer will be recorded as degree. The mean of three successful measurements will be used. For lumbar curvature, the sacrum and iliac crest will be used as reference points to palpate the spinal processes of T12-L1 and L5-S1, respectively. The feet of the inclinometers will be placed as simultaneously as possible over T12-L1 and L5-S1. The angle on the digital display of the inclinometer will be recorded in degrees.
Gait analyses
Time Frame: 6 months
The spatiotemporal parameters of gait will be evaluated using the Diagnostic Support Baropodometer Footscan® 3D system. The spatial parameters of gait, step length (cm), step width (cm) and foot angle (degrees) and the temporal parameters of gait, speed (m/min), cadence (step/min) and stance time (sec) will be recorded. For evaluating of the plantar pressure distribution will be used the Diagnostic Support Baropodometer Footscan® 3D system, besides the dynamic evaluation and recording of the spatiotemporal parameters, the data on the total load on the forefoot, midfoot and hindfoot; the average pressure; and the distribution of load in the forefoot, midfoot and hindfoot will be also obtained.
Trunk position sense
Time Frame: 6 months
Trunk position sense, as indicated by trunk reposition errors (TRE), will be assessed with a digital inclinometer (Acumar®,Dual Digital Inclinometer, Lafayette Instrument Company, IN, USA). The participants will be asked to stand upright in a comfortable position. The inferior angle of the scapula will first palpated as a bony landmark to find the spinousprocess of T4. After the placement of the inclinometer over the spinous process of T4, the participants will be asked to flex the trunk approximately 30° in the sagittal plane and hold this position for 3 s in eyes closed position. After returning to the neutral upright position, they will be asked to duplicate the previously attained position and held the position for 3 s for five times in a row. The absolute differences between the original position and the other five attempts will be recorded. The highest and lowest scores will be discarded and the mean of the tree remaining scores will be used to assess the trunk position sense.
Secondary Outcomes
- Lumbopelvic stabilization assessment(6 months)
- Bath Ankylosing Spondylitis Disease Activity Index(6 months)
- Disease-Related Functional Status(6 months)
- Stabilometric test(6 months)
- Bath Ankylosing Spondylitis Metrology Index(6 months)
- Disease-Related Quality of Life(6 months)
- Musculoskeletal Health Questionnaire(6 months)