SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine
- Registration Number
- NCT01250418
- Lead Sponsor
- Northwestern University
- Brief Summary
The study question: Does the SNAP-Index (SI) correlates better with the OASS than the BIS Monitor during sedation with ketamine?
The study hypothesis: Since the SNAP II monitor seems to be more responsive during emergence of anesthesia, it will have a better correlation with the OASS than the BIS monitor with the use of ketamine.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Female
- Target Recruitment
- 25
Inclusion Criteria
- Age : 18-64 years
- ASA : I-III
- Procedure : Breast or gynecological surgery
- Anesthesia :Monitored anesthesia care
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Exclusion Criteria
-
Pregnancy
-
Breast Feeding
-
Body Mass Index >35kg/m2
-
Drug or Alcohol abuse
-
Use anticonvulsants
-
History of CVA
-
Drop-out criteria:
- Patient or surgeon request
- Conversion to general anesthesia
- Inability to obtain data from both monitors
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Ketamine Group Ketamine group ketamine bolus of 0.25mg/kg followed by an infusion set at 1.5 mcg /kg/min.
- Primary Outcome Measures
Name Time Method TcCO2 Above 50 Intraoperative, an average of about 1 and 1/2 hours. % Time Tosca Monitor (TcCO2) above 50. A TcCo2 above 50 is indicative of hypoventilation.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Northwestern Memorial Hospital
🇺🇸Chicago, Illinois, United States