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Clinical Trials/NCT07480759
NCT07480759
Completed
Not Applicable

Low Load Blood Flow Restriction Training Versus Traditional Heavy Load Resistance Training in Male Athletes With Sub-acute Non-specific Low Back Pain

University of Lahore1 site in 1 country64 target enrollmentStarted: November 10, 2025Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
University of Lahore
Enrollment
64
Locations
1
Primary Endpoint
Numeric Pain Rating Scale (NPRS) for Pain Intensity in Sub-Acute Non-Specific Low Back Pain

Overview

Brief Summary

his randomized clinical trial aims to compare the effects of low-load blood flow restriction (LL-BFR) training and traditional heavy-load resistance training (HL-RT) on male athletes with sub-acute non-specific low back pain. Participants will be randomly assigned to either the LL-BFR or HL-RT group for a specified intervention period. Both groups will perform supervised exercise sessions targeting core and lumbar stabilizing muscles. Outcomes including pain intensity, functional disability, and muscle strength will be assessed at baseline and post-intervention. The study seeks to determine whether LL-BFR can provide comparable or superior benefits to HL-RT while reducing mechanical stress on the lumbar spine.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 24 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • • Male athletes (Liu et al., 2025)
  • Age 18-24 years (Liu et al., 2025)
  • Athletes like wrestlers, weightlifters and sprinters
  • Report pain and discomfort localized below the costal margin and above the inferior gluteal folds. (Adhikari et al., 2021)
  • Subacute low back pain - Pain lasting between 4 to 12 weeks. (Chou \& Atlas, 2023)
  • Participants with moderate level of pain on Visual analogue scale.(Nambi et al., 2022)
  • Negative straight-leg-raising (SLR) test, which is useful for diagnosing lumbar disc herniation. (Jardim et al., 2022)
  • No dominant leg pain from radicular or cauda equina disorders. (Liu et al., 2025)
  • No history of previous lumbar or thoracolumbar spine surgery. (Jardim et al., 2022)

Exclusion Criteria

  • Any prior lumbar or thoracolumbar spine surgery (Liu et al., 2025)
  • A history of cancer, spinal infection, rheumatologic diseases, spine fracture, red flag signs (such as significant and unexplained weight loss exceeding 10% of total body weight within the past six months, and presence of fever), psychological disorders, and previous spine surgery, radiculopathy, anatomical or congenital abnormalities. (Hernandez-Lucas et al., 2023)
  • History of peripheral arterial disease or deep vein thrombosis. (Jardim et al., 2022)

Arms & Interventions

Low Load Blood Flow Restriction Training (LL-BFR)

Experimental

Intervention: Low Load Blood Flow Restriction Training (LL-BFR) (Other)

Low Load Blood Flow Restriction Training (LL-BFR)

Experimental

Intervention: Traditional Heavy Load Resistance Training (HL-RT) (Other)

Traditional Heavy Load Resistance Training (HL-RT)

Active Comparator

Intervention: Low Load Blood Flow Restriction Training (LL-BFR) (Other)

Traditional Heavy Load Resistance Training (HL-RT)

Active Comparator

Intervention: Traditional Heavy Load Resistance Training (HL-RT) (Other)

Outcomes

Primary Outcomes

Numeric Pain Rating Scale (NPRS) for Pain Intensity in Sub-Acute Non-Specific Low Back Pain

Time Frame: Baseline and 4 weeks

Pain intensity in participants with sub-acute non-specific low back pain will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point self-reported pain scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Participants will be asked to rate their average low back pain during the past 24 hours by selecting a number from 0 to 10.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
University of Lahore
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mahnoor Ijaz

Principal Investigator

University of Lahore

Study Sites (1)

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