Comparative evaluation of clinical and radiological parameters following the use of biphasic alloplastic material with Amniotic membrane / Collagen membrane for the management of periodontal intra-bony defects - A prospective double blind randomized controlled clinical trial.

nivedhav0 sites20 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

March 13, 2020

Last Updated

4 years ago

Study Type

Interventional

Sponsor

nivedhav

•1 Age 21\-50 years
•2 Patients with moderate to severe localized periodontitis with a Probing Depth (PD) \>\=6 mm and an intrabony component of more than 3 mm as detected on Intra oral periapical radiographs (IOPAR) and bone sounding (Sali 2016\).
•3 Intrabony defect angle of less than 40 degree (Sali 2016\).
•4 Circumferential defect with interdental intrabony defect depth of more than 3mm will be included.
•5 Nonsmoker (Never smoker) or former smoker (Does not smoke now and has not smoked at all for a minimum of the last 12 consecutive months)

•1 Current Smokers (smokers who have smoked more than 100 cigarettes in their lifetime and currently smoke)
•2 Systemic chronic conditions known to be associated with periodontitis or with changes in systemic inflammation: Diabetes, Cardiovascular diseases, Rheumatoid Arthritis, Rheumatic Fever, SLE, Malignancy, Respiratory diseases, Renal diseases, Other (e.g., autoimmune diseases, fungal infections, immunological deficiencies, etc.)
•3 Pregnant / Lactating mothers
•4 Previous History of periodontal treatment at the selected site
•5 Teeth with intrabony defect component and furcation involvement were also excluded from the study.