Exploratory clinical study on effects to the blood flow and safety of transcutaneous application of carbon dioxide for fractured limbs
Not Applicable
- Conditions
- fracture
- Registration Number
- JPRN-UMIN000013641
- Lead Sponsor
- Kobe University Graduate School of Medicine
- Brief Summary
ineteen patients were subjected to complete analysis. No adverse events were observed. Arterial and expired gas analyses revealed no adverse systemic effects including hypercapnia. The mean ratio of blood flow 20 min after CO2 therapy compared with the pre-treatment level increased by approximately 2-fold in a time-dependent manner.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Pathological fracture Peripheral artery disease or ischemia in the fractured limb Skin disease in the fractured limb Infection in the fractured limb Inadequate condition both general and local No written informed consent Patients who are judged as contraindication with any reasons by the doctors in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Validation of accelerating effects to the blood flow of transcutaneous application of carbon dioxide for fractured limbs
- Secondary Outcome Measures
Name Time Method Validation of safety of transcutaneous application of carbon dioxide for fractured limbs