The effects of olive-derived hydroxytyrosol intake on LDL-cholesterol oxidative suppression - A systematic review.
- Conditions
- Adult volunteers who are healthy or have no more than one mild health disorder (pertaining to blood glucose level, blood pressure or plasma lipid) which is within boundary range and not exceeding boundary range.
- Registration Number
- JPRN-UMIN000040080
- Lead Sponsor
- Maruzen Pharmaceuticals Co., LTD.
- Brief Summary
We included three articles as result of searching on databases and judging with including criteria. The articles reported result of randomized double-blinded placebo-controlled crossover study which evaluated effect of intake olive derived hydroxytyrosol on blood oxLDL concentrate. We judged heterogeneity of these articles were low and performed meta-analysis. We concluded intake olive derived hydroxytyrosol is significantly decrease blood oxLDL concentrate.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 249
Not provided
Literature which does not meet key inclusion criteria will be excluded. Subjects who are suffering from illness, overweight (BMI is 30kg/m2 or more), planning or currently pregnant or breastfeeding, and children (persons under 18 years), will be excluded from this study. If subjects have conditions which exceed limits: Mild hyperlipidemia, Stage 1 hypertension, or Mild hyperglycemia, and/or have more than one of these conditions, the subject is deemed as having an illness and excluded.
Study & Design
- Study Type
- Others,meta-analysis etc
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome is the amount of serum oxidized LDL-cholesterol.
- Secondary Outcome Measures
Name Time Method