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临床试验/NCT02155153
NCT02155153已完成不适用

The Effect of Gum Chewing on the Duration of Postoperative Ileus and Total Length of Hospital Stay After Reversal of Ileostomy

Services Hospital, Lahore2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2014年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
100
试验地点
2
主要终点
passage of flatus

研究概览

简要总结

Postoperative ileus is generally referred to as the transient impairment of bowel motility after abdominal or other surgery and diagnosed by postoperative abdominal pain vomiting constipation and distension.

The potential complications of prolonged POI include increased postoperative pain, increased nausea and vomiting, pulmonary complications, poor wound healing, delay in resuming oral intake, delay in postoperative mobilization, prolonged hospitalization, and increased health-care costs. The estimated economic impact of POI in the United States is $7.5 billion per year, excluding the expenses of work loss.

In view of these complications and economic burden a number of pharmacologic and non-pharmacologic strategies have been adopted by the doctors all over the world to reduce the burden of postoperative ileus.These programs involve transverse or curved surgical incisions, removal of nasogastric tubes at the end of anesthesia, intraoperative and postoperative analgesia, early postoperative feeding, mobilization, and gum chewing.

The use of gum chewing has emerged as a new and simple modality for decreasing POI. And reviews have concluded that there is consistent benefit for patients from gum chewing after the intestinal surgery; colonic surgery and gynecological surgery.

This study is based on the hypothesis that postoperative gum chewing is beneficial in prevention of postoperative ileus after reversal of ileostomy.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
15 Years 至 60 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Patients of either gender with age ranging from 15 to 60 years.
  • Patients whose ileostomies were made for typhoid or tuberculous perforation
  • Patients with no distal obstruction on loopogram.

排除标准

  • Patients with age less than 15 years and greater than
  • Patients having co-morbid factors such as diabetes and ischemic heart disease.
  • Patients whose ileostomy was made for any condition other than typhoid or tuberculosis.

结局指标

主要结局

passage of flatus

时间窗: within 48 hours after the operation

次要结局

未报告次要终点

研究者

发起方
Services Hospital, Lahore
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Dr. SamiUllah

Medical Officer

Services Hospital, Lahore

研究点 (2)

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