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Multicenter, openlabel, noncomparative, clinical decision basedpostmarketing surveillance (PMS) study forEvaluation of efficAcy and Safety of Xolair (Omalizumab)in IgE mediated Asthma in Pediatric patients

Phase 4
Conditions
Health Condition 1: null- All male & female pediatric and adolescents patients (age range 6 and 18 years) withmoderate to severe persistent allergic asthma
Registration Number
CTRI/2013/03/003478
Lead Sponsor
ovartis Healthcare Private limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

1.Male or Female, 6 and 18 years of age

2. With inadequately controlled moderate to severe persistent allergic asthma (GINA Stage IV)

a. A positive Skin Prick Test or RAAST Test to greater than or equal to 1periennial aeroallergen, or strong clinical

history

b. IgE levels greater than or equal to 30 less er than or equal to 1500 IU per mL

c. Continuous treatment with high dose ICS plus LABA 2 severe exacerbations per year

d. Require more than 2 courses of oral corticosteroids in year

e. Regular disruptive nocturnal or daytime symptoms as per GINA Stage IV

Exclusion Criteria

1.Patients that have been treated with Xolair in the past 18 months.

2. Severe medical condition(s) that in the view of the physician prohibits participation in the study

e.g. severe renal or hepatic impairment

3. Known hypersensitivity to Xoalir (Omalizumab) or any of the components in the formulation

Study & Design

Study Type
PMS
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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