Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste

Not Applicable

• Conditions: Caries
• Interventions: Other: Miswak toothpaste; Other: Fluoride toothpaste

• Registration Number: NCT05109299
• Lead Sponsor: Cairo University

Brief Summary

Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.

Detailed Description

This study is a randomized clinical trial, with parallel study design, 1:1 allocation ratio and superiority framework. The aim of the current trial is to evaluate antibacterial effect miswak toothpaste compared to fluoride toothpaste in high caries risk patients.

Study Timeline

• Status Verified: 2021-10
• Study First Submitted: 2021-10-15
• Study First Submitted QC: 2021-10-26
• Last Update Submitted: 2021-10-26
• Study First Posted: 2021-11-05
• Last Update Posted: 2021-11-05
• Study Start: 2021-12-01
• Primary Completion: 2022-03-30
• Study Completion: 2022-04-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• High caries risk patients.
• At least one carious tooth according to CAT caries risk assessment model.
• Patient compliance

Exclusion Criteria

• Participant in another trial.
• Using another antimicrobial agents since one month of sampling.
• Systemic diseases or concomitant medication affecting salivary flow.
• Parafunctional habits.
• Pregnancy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Miswak toothpaste	Miswak toothpaste	Dabur meswak herpal toothpaste
Fluoride toothpaste	Fluoride toothpaste	Signal fluoride toothpaste, containing 1450 ppm of fluoride

Primary Outcome Measures

Name	Time	Method
streptococcus mutans count	3 months	Counting streptococcus mutans, Measurement: Mitis-Salivarius agar plate, Unit: CFUs/mL

Trial Locations

Locations (1)

Faculty of Dentistry, Cairo University; 🇪🇬 Cairo, El Manial, Egypt