Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste

Not Applicable

• Conditions: Caries

• Registration Number: NCT05109299
• Lead Sponsor: Cairo University

Brief Summary

Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.

Detailed Description

This study is a randomized clinical trial, with parallel study design, 1:1 allocation ratio and superiority framework. The aim of the current trial is to evaluate antibacterial effect miswak toothpaste compared to fluoride toothpaste in high caries risk patients.

Study Timeline

• Status Verified: 2021-10
• Study First Submitted: 2021-10-15
• Study First Submitted QC: 2021-10-26
• Last Update Submitted: 2021-10-26
• Study First Posted: 2021-11-05
• Last Update Posted: 2021-11-05
• Study Start: 2021-12-01
• Primary Completion: 2022-03-30
• Study Completion: 2022-04-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• High caries risk patients.
• At least one carious tooth according to CAT caries risk assessment model.
• Patient compliance

Exclusion Criteria

• Participant in another trial.
• Using another antimicrobial agents since one month of sampling.
• Systemic diseases or concomitant medication affecting salivary flow.
• Parafunctional habits.
• Pregnancy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
streptococcus mutans count	3 months	Counting streptococcus mutans, Measurement: Mitis-Salivarius agar plate, Unit: CFUs/mL

Trial Locations

Locations (1)

Faculty of Dentistry, Cairo University; 🇪🇬 Cairo, El Manial, Egypt