Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste in High Caries Risk Patients: Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- streptococcus mutans count
研究概览
简要总结
Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.
详细描述
This study is a randomized clinical trial, with parallel study design, 1:1 allocation ratio and superiority framework. The aim of the current trial is to evaluate antibacterial effect miswak toothpaste compared to fluoride toothpaste in high caries risk patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •High caries risk patients.
- •At least one carious tooth according to CAT caries risk assessment model.
- •Patient compliance
排除标准
- •Participant in another trial.
- •Using another antimicrobial agents since one month of sampling.
- •Systemic diseases or concomitant medication affecting salivary flow.
- •Parafunctional habits.
- •Pregnancy.
研究组 & 干预措施
Fluoride toothpaste
Signal fluoride toothpaste, containing 1450 ppm of fluoride
干预措施: Fluoride toothpaste (Other)
Miswak toothpaste
Dabur meswak herpal toothpaste
干预措施: Miswak toothpaste (Other)
结局指标
主要结局
streptococcus mutans count
时间窗: 3 months
Counting streptococcus mutans, Measurement: Mitis-Salivarius agar plate, Unit: CFUs/mL
次要结局
未报告次要终点
研究者
Omar Osama Shaalan
Lecturer, Conservative Dentistry Department, Faculty of Dentistry
Cairo University