Study on the effect of caffeine intake on tear production and its correlation with genetic variatio
Not Applicable
- Conditions
- Dry eye
- Registration Number
- JPRN-UMIN000002903
- Lead Sponsor
- niversity of Tokyo Hospital, Department of Corneal Transplantation
- Brief Summary
Arita R, Yanagi Y, Honda N, Maeda S, Maeda K, Kuchiba A, Yamaguchi T, Yanagihara Y, Suzuki H, Amano S. Caffeine increases tear volume depending on polymorphisms within the adenosine A2a receptor gene and cytochrome P450 1A2. Ophthalmology119:972-978, 2012
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with dry eye of moderate degree or more. Schirmer test value of 5 mm or less. Tear breakup time of 5 seconds or less.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tear meniscus height
- Secondary Outcome Measures
Name Time Method