Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 96
- 试验地点
- 1
- 主要终点
- Perceptual Phase
研究概览
简要总结
Using Psychophysics Methods for Quantitative Assessment of Sensory Binocular Imbalance After Cataract Surgery
详细描述
Using binocular phase combination paradigms and binocular rivalry paradigms to quantitatively assess the degree of sensory binocular imbalance in patients following cataract surgery, investigating the relationship between unilateral and bilateral cataracts in children and varying severities of cataracts in adults with respect to sensory ocular dominance, and forecasting the postoperative quality of life for patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 90 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages between 6 and 90 years old, and the individual or legal guardian is capable of understanding and voluntarily signing an informed consent form;
- •No history of ocular trauma or intraocular surgery, no physical or medical treatments have been undergone, and the clinical diagnosis in the medical records is age-related, congenital, or developmental cataract patients;
- •Best-corrected visual acuity in both eyes is greater than 0.8 before the study, fusion ability is normal as checked by Worth's 4-dot test, and at least 1 month has passed since the last surgery;
- •Good communication skills and the ability to understand and grasp the trial;
- •No significant contraindications to surgery found in preoperative systemic and ocular examinations.
排除标准
- •Patients with traumatic or complex cataracts;
- •Those diagnosed with glaucoma before or after surgery;
- •Individuals with a history of intraocular surgery (such as vitrectomy) or laser treatment;
- •Exclude those with severe ocular comorbidities (including microphthalmia, aphakia, anterior segment dysgenesis, uveitis, optic nerve dysplasia, retinopathy of prematurity, congenital glaucoma, etc.) and severe systemic comorbidities (including syndromes affecting connective tissue function, such as Marfan syndrome, homocystinuria, or Down syndrome, severe birth defects, and epilepsy);
- •Any systemic diseases related to the eyes, such as rheumatic immune diseases;
- •Those with surgical records indicating any severe intraoperative complications during cataract surgery;
- •Individuals who cannot cooperate with the examination.
结局指标
主要结局
Perceptual Phase
时间窗: Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour.
The perceptual phase when the interocular contrast between the two eyes is 1.
Ocular Dominance Index (ODI)
时间窗: Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour.
The ratio of the total time spent by the observer reporting complete dominance of visual stimuli presented to the dominant or non-dominant eye.
次要结局
未报告次要终点
研究者
Yune Zhao
Vice president of Eye Hospital of Wenzhou Medical University
Wenzhou Medical University