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Exercise Interventions on Problematic Mobile Phone Use: a Multi-arm Randomized Controlled Trial

Completed
Conditions
Tai Chi Chuan
Intestinal Flora
Randomized Clinical Trial
Exercise Intervention
Interventions
Behavioral: aerobic exercise or Tai Chi Chuan interventions
Registration Number
NCT05843591
Lead Sponsor
Anhui Medical University
Brief Summary

Problematic mobile phone use (PMPU) has been described as a growing public health issue. This randomized controlled trial aimed to determine if aerobic exercise or Tai Chi Chuan as compared to the wait-list control group decreased PMPU-related symptoms; and to analyze the composition of the intestinal flora in the three study groups to explore the correlation between PMPU scores and flora species. A consecutive sample of 90 college students with PMPU was randomized to the aerobic exercise group (AE group, n = 30), the Tai Chi Chuan group (TCC group, n = 30), or the wait-list control group (WLC group, n = 30). The primary outcome was addiction symptoms, i.e., the PMPU score as assessed by the Smartphone Addiction Scale-Short Version (SAS-SV). Secondary outcomes were the emotion-related symptoms (depression, anxiety, self-esteem and self-efficacy), and physical-related symptoms (sleep quality, physical-fatigue and mental-fatigue). Intervention effects were analyzed via generalized estimated equation analysis (GEE).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
90
Inclusion Criteria
  • (1) be 18 years or older; (2) college students; (3) fulfill the Smartphone Addiction Scale-Short Version (SAS-SV) criteria for PMPU; (4) have a low level of daily physical activity.
Exclusion Criteria
  • (1) regular practice of moderate and higher intensity exercise (Physical activity was measured using the Physical Activity Rating Scale-3 (PARS-3), which is a 3-item self-reported scale comprising intensity, duration and frequency [14]. Exercise was considered to be of more than moderate intensity when the PARS-3 scores was >42); (2) any major disease (cardiovascular disease, respiratory illness, and musculoskeletal disorder) that can affect them to participate in exercise training; (3) any gastrointestinal diseases and other diseases affecting intestinal bacteria; and (4) any severe mental illness (e.g., depression, anxiety, bipolar disorder, obsessive-compulsive disorder, eating disorder, and post-traumatic stress disorder).

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Wait-List Control groupaerobic exercise or Tai Chi Chuan interventionsParticipants in the wait-list control (WLC) group received no intervention in addition to their usual physical education classes.
Tai Chi Chuan groupaerobic exercise or Tai Chi Chuan interventionsParticipants in the Tai Chi Chuan (TCC) group attended an 8-week Tai Chi training program, which consists of 24-form Tai Chi and Bafa Wubu of Tai Chi. Certified instructors administer and guide Tai Chi Chuan activities. We set up 6 Tai Chi Chuan classes each week, and participants in the Tai Chi Chuan group can participate in any 3 of the 6 classes each week to be considered as completing the task. Each 1-hour training session consists of a brief warm-up stretching session followed by standard Tai Chi routine activities.
Aerobic Exercise groupaerobic exercise or Tai Chi Chuan interventionsParticipants in the aerobic exercise (AE) group were asked to perform moderate to high intensity regular aerobic exercise. Exercise was required 3 times per week for at least 1 hour each time. At the beginning of the exercise, they were required to sign in at the research personnel, and at the end of the exercise, they were also required to sign out at the research personnel. However, there was no restriction on the type of exercise, which could be running, basketball, badminton, table tennis, tennis, rope skipping, dancing, etc.; there was no restriction on the form of exercise, which could be individual or group exercise; there was no restriction on the period of exercise start, which could be any time of the day to start exercise.
Primary Outcome Measures
NameTimeMethod
Smartphone Addiction Scale-Short Version (SAS-SV)2 months

Problematic mobile phone use levels

Secondary Outcome Measures
NameTimeMethod
Zung's Self Rating Depression Scale (SDS)2 months

Depression levels

Zung's Self-Rating Anxiety Scale (SAS)2 months

Anxiety levels

Intestinal flora2 months

Fecal microbial DNA was extracted using the QIAamp Fast DNA Stool Mini kit (Qiagen, Hilden, Germany) according to the manufacturer's instructions. All procedures of DNA extraction were performed in a class II biosafety cabinet. Universal primers (341F and 805R) linked with indices and sequencing adaptors were used to amplify the V3-V4 regions of the 16S rRNA gene. The amplification products were detected by agarose gel electrophoresis, and the amplification products were purified by nucleic acid purification beads to obtain the original library of the sample. The library quality was assessed on the Agilent Bioanalyzer 2100 system. The 16S rRNA gene amplification products sequencing was performed with the 2 × 250 bp paired-end method using the Illumina MiSeq Benchtop Sequencer \[48\] at the Genesky Biotechnologies Inc. (Shanghai, China).

Rosenberg self-esteem scale (RSES)2 months

Self-esteem levels

General Self-Efficacy Scale (GSES)2 months

Self-Efficacy levels

Pittsburgh Sleep Quality Index (PSQI)2 months

Sleep Quality levels

Fatigue Scale-142 months

physical and mental fatigue levels

Trial Locations

Locations (1)

Anhui Medical University

🇨🇳

Hefei, Anhui, China

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