Evaluation of the effectiveness of an ankle-foot orthosis on the walking ability and coordination in patients with Huntington's Disease

• Conditions: chorea major; Huntington's chorea; 10028037

• Registration Number: NL-OMON31882
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

* 20 years of age or older
* clinically diagnosed with Huntington's disease
* eligible to wear AFO according to the clinical process in Overduin.
* able to walk a minimum of 2 minutes continuous on a level surface

Exclusion Criteria

* being diagnosed with orthopedic, neurologic or other conditions other than Huntington's disease, wich can influence gait.
* not being able to understand instructions.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- times measured with the ten meter test and the *Timed up-and-go* test<br /><br>- size of stridevariability (standard deviation)<br /><br>- composition of stridevariability (DFA)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- intensity of arm- and legmovements (maximum and average acceleration)<br /><br>- regularity in arm- and legmovements (sample entropy)<br /><br>- local stability of arm-and legmovements (greatest lyapunov exponent)<br /><br>- questionaire</p><br>