Pain management in rheumatoid arthritis.

Phase 4

• Conditions: Health Condition 1: M057- Rheumatoid arthritis with rheumatoid factor without organ or systems involvement

• Registration Number: CTRI/2020/04/024778
• Lead Sponsor: All India Institute of Ayurveda

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients with pratyatma lakshana of Amavata (e.g. Angamarda, shotha, sandhishool, stabhata, Trishna, Alasye, Aruchi, gaurava, jawara, apaka sparshaasahata) specially with impaired jatharagani and dhatuagani.

2. The 2010 American College of Rheumtology/ European League Against Rheumatism.

3. Able and willing to give written informed consent.

Exclusion Criteria

1. Patients with other systemic complications of RA like RHD, Rheumatic fever, pleural â??pericardial disease.

2. Patients with poorly controlled Hypertension ( >160/100 mm of Hg).

3. Patients with Diabetes Mellitus {B.S. (F) > 126 mg% and / or B.S. (2 hr. PP) >200 mg% OR HbA1c > 6.5%}

4. Patients diagnosed with other arthritis like gouty arthritis, tuberculous arthritis etc.

5. Patients who are unable to walk without support and / or confined to wheel chair.

6. Patients on prolonged medication with NSAIDs, analgesics or any other drugs that may have an influence on the outcome of the study.

7. Patients who have a past history of Atrial Fibrillation, Acute Coronary Syndrome, Myocardial Infarction, Stroke or Severe Arrhythmia in the last 6 months.

8. Patients with concurrent serious hepatic disorder or Renal Disorders. Severe Pulmonary Dysfunction or any other condition that may jeopardize the study.

9. H/o hypersensitivity to any of the trial drugs or their ingredients.

10. Pregnant / lactating woman.

11. Patients who have completed participation in any other clinical trial during the past 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Relieve in the impaired jatharagani and dhatuagani. <br/ ><br>2. Relieve in signs and symptoms of amavata.Timepoint: 37-40 days

Secondary Outcome Measures

Name	Time	Method
Improvement in the quality of life with the help of questionnaires for scaling of <br/ ><br>W.H.O quality of life. <br/ ><br>Timepoint: 37-40 days