NCT03499587
Active, not recruiting
Not Applicable
Effects of Maternal Obesity on Offspring Brain Development
Arkansas Children's Hospital Research Institute1 site in 1 country13 target enrollmentMarch 21, 2018
ConditionsHealthy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- Arkansas Children's Hospital Research Institute
- Enrollment
- 13
- Locations
- 1
- Primary Endpoint
- Determine whether maternal obesity correlates with abnormal brain development in newborns
- Status
- Active, not recruiting
- Last Updated
- 6 months ago
Overview
Brief Summary
The goal of this study is to see if there are negative effects of maternal obesity during pregnancy on offspring's brain development.
Detailed Description
This study will recruit pregnant women who are either obese or normal weight and otherwise healthy. We will measure their body composition, food intake and other characteristics during pregnancy. When their babies are born, we will evaluate the brain development of their babies using magnetic resonance imaging and electroencephalography at age two weeks. We will then compare the findings and see if their are differences.
Investigators
Eligibility Criteria
Inclusion Criteria
- •BMI 18.5-25 or \>30 with early OB visit medical records accessible
- •singleton pregnancy
- •about 36wks of pregnancy
- •at least 18 years of age
Exclusion Criteria
- •hypertension, diabetes, or other preexisting medical conditions
- •medications known to influence fetal growth
- •recreational drugs, nicotine or tobacco use of alcohol use while pregnant
- •pregnancy conception with assisted fertility treatment
- •medical complications developed during pregnancy
Outcomes
Primary Outcomes
Determine whether maternal obesity correlates with abnormal brain development in newborns
Time Frame: 2 weeks
Brain will be imaged at 2wks using an MRI
Study Sites (1)
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