Evaluation of the Efficacy of Transcranial Direct Current Stimulation in the Treatment of Cognitive Symptomatology in the Early Stages of Psychosis
- Conditions
- SchizophreniaF03.700.750
- Registration Number
- RBR-2t3hfv
- Lead Sponsor
- niversidade Federal de Sao Paulo - UNIFESP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Subjects of both genders, diagnosed with schizophrenia in early stage psychosis (first five years of illness), confirmed through the Structured Interview of the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders - 5th edition (SCID-5); aged 18-60 years; minimum of 4 years of education; Intelligent Quotient (IQ) from low average to higher scores (IQ>70); and the subjects should be receiving stable doses of antipsychotics for at least four weeks (antipsychotic dose stability criterion).
(1) presence of a history of cranioencephalic trauma with loss of consciousness with a time greater than 5 minutes; (2) history of central nervous system diseases that affect the brain; (3) unstable clinical conditions; (4) use of drugs that affect cognitive performance such as benzodiazepines and anticholinergic agents; (5) current diagnosis of substance abuse; (6) history of substance dependence in the last 6 months, except nicotine addiction; (7) current diagnosis of another Axis I condition, confirmed through SCID-5.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The aim of the present study protocol is to evaluate the efficacy of tDCS in the treatment of cognitive symptomatology in the early stages of psychosis.
- Secondary Outcome Measures
Name Time Method The secondary outcomes will be the positive and negative symptoms.