Comparing the effect of vitamin A ointment and Liposic gel for prevention of corneal abrasio

Not Applicable

• Conditions: Corneal abrasion.; Injury of conjunctiva and corneal abrasion without foreign body; S05.0

• Registration Number: IRCT20180107038251N4
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 November 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients older than 18 years and less than 75 years
Patients undergoing non-ocular surgery with general anesthesia
No obvious damage to face and eyes
Lack of recent hospitalization in intensive care unit
No eye damage before surgery according to the patient
No eye diseases (keratitis, keratopathy, glaucoma and other eye diseases)
American Society Of Anesthesiologist Physical status I and II
Patients with endotracheal intubation
Duration of surgery between 60-300 minutes
Supine position during surgery
No allergy to fluorescein
No pregnancy
Negative preoperative fluorescein staining
No severe systemic diseases
Do not use drugs that affect the production of tears in a recent month

Exclusion Criteria

Head and neck surgery
Death during surgery
Lack of patient cooperation and inability to answer questions related to ocular symptoms after surgery
Need for invasive interventions and hospitalization in intensive care units
End of surgery before 60 minutes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Corneal abrasion. Timepoint: Immediately after anesthesia, when leaving the recovery room, 24 hours after surgery. Method of measurement: Fluorescein paper and a flashlight with a cobalt blue light filter are used to assess corneal abrasion.

Secondary Outcome Measures

Name	Time	Method
Ophthalmic discomfort. Timepoint: 24 hours after surgery. Method of measurement: Questionnaire.