Comparisons Between Low Thoracic and Lumbar Epidural Analgesia on Postoperative Pain Low Thoracic v.s. Lumbar Epidural for Post-cesarean Pain

Not Applicable

Completed

• Conditions: Post-cesarean Pain Control Quality
• Interventions: Procedure: lumbar epidural; Procedure: low thoracic epidural

• Registration Number: NCT03946982
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Whether low thoracic epidural analgesia improves postoperative cesarean pain qualities than conventional lumbar epidural analgesia?

Detailed Description

Postoperative pain remains the leading cause of concern in women faced with undergoing a cesarean delivery. Inadequate acute pain management is associated with numerous negative effects, including delayed postpartum recovery, interference with mother-child bonding because postoperative pain limits breastfeeding, and a high risk of postpartum depression and persistent pain.

Epidural analgesia (EA) is being increasingly preferred to systemic opioid because of better analgesic effect. Although EA is widely used for cesarean delivery, the effect of the site of epidural catheter insertion on the quality of postoperative pain management remains inadequately investigated. For example, placement of the epidural catheter in the low thoracic intervertebral spaces may be more suitable for catheter-incision-congruent analgesia during caesarean delivery than in the lumbar intervertebral space; however, epidural catheter insertion is conventionally recommended at the lumbar intervertebral space. Therefore, in this study, we aim to investigate the difference in post-cesarean pain control quality between low thoracic EA and lumbar EA.

Study Timeline

• Study First Submitted: 2019-05-09
• Study First Submitted QC: 2019-05-09
• Study First Posted: 2019-05-13
• Study Start: 2019-05-28
• Status Verified: 2020-05
• Primary Completion: 2021-03-27
• Study Completion: 2021-04-30
• Last Update Submitted: 2021-06-27
• Last Update Posted: 2021-06-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 189

Inclusion Criteria

Not provided

Read More

Exclusion Criteria

Not provided

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lumbar epidural patient controlled epidural analgesia	lumbar epidural	-
Low thoracic epidural morphine	low thoracic epidural	-
Low thoracic patient controlled epidural analgesia	low thoracic epidural	-
Lumbar epidural morphine	lumbar epidural	-

Primary Outcome Measures

Name	Time	Method
Pain intensity	postoperative two days	pain intensities in three category, namely static, dynamic and uterine cramping, gauged by a 100 mm visual analogue scale
Proportion of women with a visual analogue scale> 33 mm	postoperative two days

Secondary Outcome Measures

Name	Time	Method
Adverse effects	postoperative two days	Incidences of epidural-related adverse effects including sedation states, sensory blockade, motor blockade, pruritus, nausea and vomiting

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan