NL-OMON50463CompletedPhase 3
Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer - Physical Activity & Memory (PAM) study
niversitair Medisch Centrum0 sites180 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Enrollment
- 180
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •Inclusion criteria for the study are: breast cancer patients adjuvantly treated
- •with chemotherapy plus or minus endocrine therapy, 2-4 years after cancer
- •diagnosis, 30-75 years of age, no indication of relapse or metastases, exercise
- •* 150 min/week self-reported cognitive problems, lower than expected
- •performance on neuropsychological testing, mastering the Dutch language and
- •willing to be randomly assigned to one of the two study arms.
Exclusion Criteria
- •We will exclude patients with known neurological conditions and/or diseases
- •that affect cognition (e.g. dementia, MS, TBI), disorders that might impede
- •exercise participation, patients with breast cancer in both breasts, contra
- •indications for MR imaging (see Appendix 2 Protocol); and patients switching
- •from Tamoxifen to aromatase inhibitors during the study period or four months
Investigators
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