To compare the efficacy of 2 standard anti-epileptic drugs valproate and levetiracetam in status epilepticus among elderly
Phase 4
- Conditions
- Health Condition 1: null- Patients with status epilepticus
- Registration Number
- CTRI/2016/05/006932
- Lead Sponsor
- ON FUNDED
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
•Patients with GCSE (more than 10 minutes of continuous convulsive seizure activity or two or more sequential seizures without full recovery of consciousness in between seizures), irrespective of etiology.
•Willing to participate.
•Age group more than 60 years.
Exclusion Criteria
•Not willing accompanying relatives/friends
•Patients having non-convulsive SE
•Liver failure, renal failure, cardiac disease (based on clinical judgment, available lab reports, ECG at presentation)
•Requiring urgent neurosurgical intervention.
•H/O allergy to drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Control of seizuresTimepoint: Control of seizures will be assessed in each subjects as soon as the study drug infusion is over. Subject will be continuously reassessed till primary outcome is arrived at.
- Secondary Outcome Measures
Name Time Method Mortality and MorbidityTimepoint: Recruitment to 1 month