NL-OMON42945已完成不适用
Trained platelets: Long term effects of Gram positive and Gram negative infections on platelet phenotype. - Trained platelets
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •>18 years
- •Following infections:
- •o Positive blood culture pathogenic Gram positive bacteria (eg. Staphylococcus aureus (at least 10 with S. aureus), Streptococci)
- •o Positive blood culture with a pathogenic Gram negative bacteria (eg. E. coli (at least 10 with E. coli), K. pneumoniae)
- •Expected duration of in-patient care of at least 3 days.
- •Signed informed consent
排除标准
- •Use of platelet function inhibitors (except aspirin)
- •Antibiotic therapy for longer than 72 hours
- •Myocardial infarction or stroke in the previous year
- •An active hematologic or solid malignancy
- •Terminal renal failure requiring dialysis
- •Insulin dependent diabetes mellitus
- •Solid organ transplant requiring anti-inflammatory medication
- •Use of anti-inflammatory agents such as prednison (>7.5mg) or use of targeted biological agents (eg. TNF-blockers, monoclonal antibodies) with the exception of NSAIDs
- •Micro-organisms that are well known contaminants in a blood culture (e.g. coagulase negative staphylococcus)
研究者
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