Visual Field Defects in Parkinson’s Disease: A Cross-Sectional Study on Their Clinical Patterns and Impact on Vision-Related Activities of Daily Living
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Dr Priti Singh
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Correlation between visual field defects and disease severity, cognitive function (MoCA), and vision-related quality of life (NEI VFQ-25)
Overview
Brief Summary
This cross-sectional observational study aims to evaluate the prevalence and clinical patterns of visual field defects in individuals diagnosed with Parkinson’s Disease. Visual impairments are increasingly recognized as significant non-motor symptoms of Parkinson’s Disease but are often underdiagnosed in routine clinical practice. The study will use standard visual field testing and cognitive assessments to explore the association between visual deficits, disease severity, and impact on vision-dependent activities of daily living. The hypothesis is that visual field defects are prevalent in Parkinson’s Disease and correlate with disease severity and functional impairment.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 40.00 Year(s) to 99.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •Diagnosed Parkinson’s Disease (Hoehn and Yahr Stage I–IV) Age above 40 years (to exclude young-onset Parkinson’s Disease) Ability to complete visual field testing and related questionnaires.
Exclusion Criteria
- •Severe cognitive impairment (as per MMSE assessment) Advanced dementia or psychiatric illness interfering with participation Ocular conditions independently causing visual field loss (e.g., advanced glaucoma, retinal dystrophies) Recent ocular surgery within the past 3 months.
Outcomes
Primary Outcomes
Correlation between visual field defects and disease severity, cognitive function (MoCA), and vision-related quality of life (NEI VFQ-25)
Time Frame: At baseline and at 9 months
Secondary Outcomes
- Identification of visual field defect subtypes using cluster analysis of perimetry data(At the end of data collection phase (Month 6–9))
Investigators
Dr Priti Singh
All India Institute of Medical Sciences, Bhopal