Visual Field Defects in Parkinson’s Disease: A Cross-Sectional Study on Their Clinical Patterns and Impact on Vision-Related Activities of Daily Living
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Correlation between visual field defects and disease severity, cognitive function (MoCA), and vision-related quality of life (NEI VFQ-25)
研究概览
简要总结
This cross-sectional observational study aims to evaluate the prevalence and clinical patterns of visual field defects in individuals diagnosed with Parkinson’s Disease. Visual impairments are increasingly recognized as significant non-motor symptoms of Parkinson’s Disease but are often underdiagnosed in routine clinical practice. The study will use standard visual field testing and cognitive assessments to explore the association between visual deficits, disease severity, and impact on vision-dependent activities of daily living. The hypothesis is that visual field defects are prevalent in Parkinson’s Disease and correlate with disease severity and functional impairment.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- Female
入选标准
- •Diagnosed Parkinson’s Disease (Hoehn and Yahr Stage I–IV) Age above 40 years (to exclude young-onset Parkinson’s Disease) Ability to complete visual field testing and related questionnaires.
排除标准
- •Severe cognitive impairment (as per MMSE assessment) Advanced dementia or psychiatric illness interfering with participation Ocular conditions independently causing visual field loss (e.g., advanced glaucoma, retinal dystrophies) Recent ocular surgery within the past 3 months.
结局指标
主要结局
Correlation between visual field defects and disease severity, cognitive function (MoCA), and vision-related quality of life (NEI VFQ-25)
时间窗: At baseline and at 9 months
次要结局
- Identification of visual field defect subtypes using cluster analysis of perimetry data(At the end of data collection phase (Month 6–9))
研究者
Dr Priti Singh
All India Institute of Medical Sciences, Bhopal