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临床试验/NCT07320092
NCT07320092已完成不适用

Comparison of the Incidence of Atelectasis Assessed by Lung Ultrasound in Patients Undergoing Surgery in Supine and Prone Positions

Istanbul University - Cerrahpasa1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2025年9月15日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80
试验地点
1
主要终点
Difference in lung ultrasound-detected atelectasis between supine and prone surgical positions

研究概览

简要总结

Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical positioning. The development of atelectasis has been associated with postoperative hypoxemia and other pulmonary complications.

Lung ultrasound (LUS) has emerged as a reliable, radiation-free bedside imaging modality for the detection and monitoring of atelectasis. LUS allows assessment of lung aeration through standardized ultrasound patterns and scoring systems, enabling dynamic evaluation in the perioperative period.

This is a prospective, observational cohort study designed to compare the incidence and severity of atelectasis in patients undergoing surgery in the supine position versus the prone position under general anesthesia. Adult patients undergoing elective surgical procedures will be enrolled. No experimental intervention will be applied, and all anesthetic and surgical management will follow routine clinical practice.

Lung ultrasound examinations will be performed at predefined time points after induction of anesthesia and before extubation. A standardized lung ultrasound protocol and scoring system will be used to assess lung aeration loss and detect the presence of atelectasis.

The primary outcome of the study is the difference in atelectasis detected by lung ultrasound between supine and prone surgical positions. The secondary outcome is the change in lung ultrasound scores over time.

This study aims to clarify the effects of supine and prone positions on perioperative atelectasis and to support the clinical use of lung ultrasound as a noninvasive monitoring tool in perioperative and anesthetic practice..

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients aged 18 years or older.
  • Patients scheduled for elective surgery under general anesthesia.
  • Patients undergoing surgery in the supine or prone position.
  • Patients able to provide informed consent.

排除标准

  • Emergency surgical procedures.
  • Pre-existing severe pulmonary disease affecting lung ultrasound assessment.
  • Hemodynamic instability requiring urgent intervention.
  • Contraindications to lung ultrasound examination.

研究组 & 干预措施

Supine Position

Patients undergoing surgery in the supine position under general anesthesia.

Prone Position

Patients undergoing surgery in the prone position under general anesthesia.

结局指标

主要结局

Difference in lung ultrasound-detected atelectasis between supine and prone surgical positions

时间窗: Perioperative (After induction of general anesthesia and before extubation)

Lung aeration will be evaluated using the Lung Ultrasound Score (LUS), a semiquantitative scoring system assessing aeration loss in 12 lung regions. In the supine position, lung ultrasound assessment will be performed along: the parasternal line (intercostal spaces 1-4 and 4-8), the anterior axillary line (intercostal spaces 1-6 and 6-12), and the posterior axillary line (intercostal spaces 1-6 and 6-12). In the prone position, lung ultrasound assessment will be performed along: the paravertebral line (intercostal spaces 1-6 and 6-12), the posterior axillary line (intercostal spaces 1-6 and 6-12), and the anterior axillary line (intercostal spaces 1-6 and 6-12). Each lung region will be scored from 0 to 3, resulting in a total LUS ranging from 0 to 36, where higher scores indicate greater loss of aeration and more severe atelectasis. Assessments will be performed after induction of general anesthesia and before extubation.

次要结局

未报告次要终点

研究者

发起方
Istanbul University - Cerrahpasa
申办方类型
Other
责任方
Principal Investigator
主要研究者

CHINARA NAMAZOVA

Research Assistant

Istanbul University - Cerrahpasa

研究点 (1)

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