ACTRN12611001210965
Completed
Phase 2
An open label phase II/III clinical trial of Ranibizumab on the effects and safety for diabetic macular oedema resistant to intravitreal triamcinolone (TAREDS)
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Diabetic macular oedema
- Sponsor
- the University of Sydney
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patient with diabetic macular oedema resistant to IVTA treatment.
- •IVTA resistance is defined as
- •\- An improvement in VA of less than 5 letters
- •\- A reduction in central retinal thickness in OCT of less than 100 microns
- •(or less than 20%, whichever is greater) 6 weeks after treatment with IVTA for at least 2 consecutive injections.
Exclusion Criteria
- •\- loss of vision due to other causes (e.g. age related macular degeneration, myopic macular degeneration)
- •\- no useful vision in fellow eye
- •\- cataract surgery or retinal laser within 1st six months of entering the study
- •\- uncontrolled systemic disease including blood pressure\>180/110
Outcomes
Primary Outcomes
Not specified
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