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Clinical Trials/ISRCTN54195799
ISRCTN54195799
Completed
N/A

Older People and Enhanced Neurocognitive function study

ondon School of Hygiene and Tropical Medicine (LSHTM) (UK)0 sites200 target enrollmentApril 4, 2008
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Conditionserve and cognitive functionNervous System DiseasesCognitive function

Overview

Phase
N/A
Intervention
Not specified
Conditions
erve and cognitive function
Sponsor
ondon School of Hygiene and Tropical Medicine (LSHTM) (UK)
Enrollment
200
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 4, 2008
End Date
TBD
Last Updated
9 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
ondon School of Hygiene and Tropical Medicine (LSHTM) (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Healthy volunteers
  • •2\. Aged 75 years and over, either sex
  • •3\. Defined low B12 status (greater than 107 pmol/l and less than 210 pmol/l)
  • •4\. No previous history of diabetes or dementia

Exclusion Criteria

  • •1\. Pre\-existing type I or type II diabetes at baseline
  • •2\. Pre\-existing dementia at baseline
  • •3\. Currently consuming vitamin B12 on a daily basis
  • •4\. Mini\-Mental State Examination (MMSE) score less than 24 at baseline screen
  • •5\. Very low B12 (below 107 pmol/l \- Beckman Coulter assay)
  • •6\. B12 levels above 210 pmol/l
  • •7\. Anaemic
  • •8\. History of epilepsy
  • •9\. Those with implanted metallic devices such as a pacemaker
  • •10\. Alcoholics

Outcomes

Primary Outcomes

Not specified

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