Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- placental vascular indices in prediction of preeclampsia
研究概览
简要总结
• Preeclampsia is a multisystem disorder that can cause considerable maternal and fetal morbidity and mortality. Late preeclampsia (with delivery >34 weeks) is more frequent and less serious than early preeclampsia (with delivery <34 weeks). Poor early placentation has been especially associated with early disease. Early identification of women at risk of preeclampsia is currently a crucial aim of antenatal care since they may benefit from prophylactic treatment and increased surveillance.
详细描述
- The introduction of three-dimensional (3D) ultrasound techniques, with the option of calculating placental volume and measuring vascular indices, has created an excellent opportunity to study early changes in the uteroplacental circulation space, which includes the maternal spiral arteries and the intervillous space. This technology may allow a more direct evaluation of the abnormal placentation process thought to herald the development of preeclampsia.
- The aim of this study was to assess the usefulness of placental volume and 3D vascular indices as reliable predictors of early preeclampsia in comparison to uterine artery Doppler
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •A. Control group: Pregnant women:
- •Age between 18-35 years
- •Parity: primigravidas and multiparas.
- •Have no history of preeclampsia or eclampsia.
- •Have no history of chronic hypertension.
- •Not diabetic.
- •Not have antiphospholipid syndrome.
- •Not have autoimmune disease such as SLE.
- •B. High risk group: Pregnant women with:
- •History of preeclampsia -Eclapmsia
- •Chronic hypertension
- •Antiphospholipid syndrome.
- •Autoimmune syndrome such as SLE.
排除标准
- •• Smoking
- •Dichorionic placentae
- •Fetal anomaly
- •Uterine fibroid at the site of placental implantation
- •Subchorionic hematoma
结局指标
主要结局
placental vascular indices in prediction of preeclampsia
时间窗: one year
placental vascular indices in prediction of preeclampsia compared to uterine artery doppler in prediction of preeclampsia
次要结局
未报告次要终点
研究者
Sherif Elsirgany
Researcher ,Family Planning and Reproductive Health Department
National Research Centre, Egypt