Vitamin D deficiency can make acne worse

Not Applicable

Completed

• Conditions: Acne; Skin and Connective Tissue Diseases

• Registration Number: ISRCTN11007935
• Lead Sponsor: Chungnam National University Hospital

Brief Summary

2016 Results article in https://pubmed.ncbi.nlm.nih.gov/27560161 (added 07/11/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-04-30
• Study Start: 2015-10-15
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

1. Adults aged between 20 and 35 years with acne
2. Adults aged between 20 and 35 years without acne (healthy controls)

Exclusion Criteria

1. Receiving therapeutic interventions such as acne treatment, systemic corticosteroids, vitamin D supplements
2. Subjects with concomitant inflammatory diseases

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum vitamin D level in patients with acne and healthy controls is measured using blood analysis of 25-hydroxy vitamin D (25(OH)D) concentration at baseline.

Secondary Outcome Measures

Name	Time	Method
<br> 1. The severity of acne was assessed using digital photographs and the global acne grading system (GAGS) score at baseline, 2, 4 and 8 weeks<br> 2. Counts of non-inflammatory lesions (comedones) and inflammatory lesions (papules, pustules, and nodules) were made at each visit, and dermatological assessments were performed blind by three independent dermatologists<br>