Clinical Study of Karveeradi Lepa in Dadru (Ringworm)

MATERIAL AND METHODS:

1.       All the classical texts will be well churned to establish the facts about Karveeradi Lepaand its application on Dadru.

2.       Thesis a Single Blind Clinical Trial.

3.       The main object of the present work is to undertake a clinical study of Karveeradi Lepain the management of Dadru.

Pharmacognostic study of Single ingredients and its authentication will be Selection of the Cases

For this clinical study, patient of age group 10 year to 50 years will be randomly selected for the study. The cases will be registered on the clinical basis and investigation from OPD and IPD of Agadtantra, Panchakarma and Kayachikitsa department of Uttaranchal done at PG Department of Dravyaguna of Uttaranchal Ayurvedic Medical College and Hospital, Dehradun as per guidelines.

UttaranchalAyurvedicMedical College and Hospital, Dehradun, Cases will be selected randomly for this clinical study irrespective of Religion, Occupation, Sex etc.

A detailed proforma will be prepared on the basis of the Ayurvedictext and allied sciences. The patient fulfilling the inclusion and exclusion criteria will be registered on this proforma and scoring of the different features will be done on the assessment criteria.

Inclusion Criteria

1.       Age group->10yearsand<50 years

2.       Sex-Both

3.       Patients diagnosed as having Dadru on the basis of classical symptoms-

a.       Kandu

b.       Pidika

c.       Raga

d.       Rukshata

e.       Utsanmandala

Exclusion Criteria

1.    Age-<10yearsand>50years

2.    Patient under long standing medication

3.    Pregnant Women

4.    Lactating Women

5.    Chronicity more than 5 years

6.    Pre-existingsk in condition

 Criteria for With-drawl

1.       Any Inter-current Illness

2.       Personal reason

3.       If any side effect occurs.

 CRITERIA FOR ASSESSMENT

The results of the therapy will be assessed on the basis of clinical signs and symptoms mentioned in Ayurvedicclassics. Functional capacity of the patients will also assess and laboratory investigations will be repeated at the end of the treatment.

Overall effect of the treatment will be assessed on the basis of the criteria given as below:

a.       CompleteRemission-100% relief

b.       MarkedImprovement-75-99% relief

c.       ModerateImprovement->50-74%relief

d.       MildImprovement->25-<49%relief

e.       NoImprovement-<25% relief

GROUPING

No Grouping because it is a Single Blind Clinical Trial.

Period– One Month

Dosing–External Application

 Scoring Criteria

The result of the therapies will be assessed on symptoms of Dadrumentioned in Ayurveda.

 

S.

No.

Symptoms

0

1

2

|1.

Kandu**(Itching)**

No Kandu

Mild (No disturbance while doing work)

Moderate (Disturbs the work)

|2.

Raga**(Erythema)**

Normal Skin

Mild Redness

Moderate Red

|  Colour

   |3.

Pidika**(Eruption)**

No pidika

Alpa pidika

Madhyama pidika

|4.

Rukshata

(Dryness)

No rukshata

Mild rukshata

Moderate rukshata

|5.

Utsannamandala**(Elevation of Lesion)**

No Mandala

Mild Mandala

Moderate Mandala

Follow-Up:

•       1stFollowup– After15thday of 2ndSitting

•       2ndFollowUp- After 1 month of 2ndSitting

 Method of Data Collection:

After the completion of treatment, the assessment will be done on same criteria as before the treatment and scoring will be done on the same pattern. The different tables of scores, obtained before treatment and after treatment, will be prepared for the comparison and statistical analysis will be done.

OBSERVATION:

The observation of the patients will be carried out before and after completion of the treatment.

Statistical Analysis

To obtain the efficacy of the therapy, proper statistical analysis will be carried out of available data.

Wilcoxon Test.

 Result: The result will be analyzed statistically and discussed.