Coeliac Disease in the Nord-Trøndelag Health Study (HUNT)
- Conditions
- Celiac Disease
- Interventions
- Diagnostic Test: Endoscopy and biopsy
- Registration Number
- NCT04041622
- Lead Sponsor
- Norwegian University of Science and Technology
- Brief Summary
In this study, all citizen of Nord-Trøndelag County, Norway, above 20 years of age are invited to participate in a population-based health study, the HUNT study. Blood samples are drawn from the participants and assessed for celiac disease by a serological assay. Celiac disease is a chronic inflammatory disease of the small intestine due to dietary gluten in wheat, barley and rye. The diagnosis will be verified through endoscopic assessment and biopsies from the small intestinal mucosa. The aims of the study are 1) to establish the population-based prevalence of celiac disease; 2) to assess the consequences of the disease from patient reported outcomes, symptoms, deficiencies, and co-morbidity; 3) to study possible risk factors and environmental triggering events; 4) to identify genetic predictors and gene-environmental interactions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 56000
- Participants of the forth round of the HUNT study
- None
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Endoscopy and biopsy Endoscopy and biopsy Participants of the HUNT study with a positive serological assay for celiac disease are invited to attain a diagnostic endoscopy with duodenal biopsies
- Primary Outcome Measures
Name Time Method Prevalence of celiac disease 1 year the proportion of cases in the general population of Nord-Trøndelag County, Norway
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Levanger Hospital, Nord-Trøndelag Hospital Trust
🇳🇴Levanger, Norway