Recovery of Serum Creatinine at Discharge Impacts Mortality

• Conditions: Kidney; Functional Disturbance
• Interventions: Other: no intervention

• Registration Number: NCT03417791
• Lead Sponsor: Guangdong Provincial People's Hospital

Brief Summary

The aim of our study is to assess the mortality in the in-hospital patients who have elevated serum creatinine. A registry of patients with increased serum creatinine during hospital was conducted at the Guangdong General Hospital from January 1st, 2007 to December 30th, 2013. The primary clinical outcome is all-cause mortality, followed from the date of hospital discharge to Dec 30th 2018. Patients were divided into three groups, according to the serum creatinine recovery ratio (discharge/max serum creatinine). All-cause mortality, including the date of death, was identified from the electronic hospitalization data, phone follow-up, and confirmed by the household registration (HUKOU) system, a record of registration required by law in China. Baseline characteristics, including primary disease diagnosis, blood pressure, major treatment, drug use and et al, were collected. Demographic data were collected from the electronic hospitalization data and electronic hospital discharge records. All co-morbid conditions were identified using International Statistical Classification of Diseases, Tenth Revision (ICD-10), coding algorithms applied to electronic physician claims and electronic hospital discharge records.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01-01
• Status Verified: 2017-11
• Study First Submitted: 2018-01-17
• Study First Submitted QC: 2018-01-24
• Last Update Submitted: 2018-01-24
• Study First Posted: 2018-01-31
• Last Update Posted: 2018-01-31
• Primary Completion: 2018-12-30
• Study Completion: 2018-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20000

Inclusion Criteria

• In-hospital patients in Guangdong General Hospital in 2007
• Age>=18y
• Patients with increased serum creatinine during hospital

Exclusion Criteria

• Death during hospital
• Diagnosed with End-stage renal disease
• given the renal replace therapy during hospital

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
kidney function recovery	no intervention	the registry and follow up of consecutive patients with increased serum creatinine during hospital in 2007

Primary Outcome Measures

Name	Time	Method
all-cause mortality	10 years	all-cause mortality

Trial Locations

Locations (1)

Guangdong General Hospital; 🇨🇳 Guangzhou, Guangdong, China