Impact of Neuropsychological Alteration of Patients With Eating Disorders

Completed

• Conditions: Eating Disorder

• Registration Number: NCT04091477
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Eating disorders are multifactorial disorders currently conceptualized in a biopsychosocial model, but pathophysiology remains relatively unknown, and robust etiological models to guide treatment are therefore lacking. Different endophenotypes and neurocognitive vulnerability factors have been found in eating disorders including decision making abnormalities. The investigators hypothesize that decision making abnormalities are associated with a lower level of functioning and quality of life which could lead to social and interpersonal difficulties. The investigators also hypothesize that these anomalies are associated with a particular clinical profile (more restrictive profile, more hyperactivity, less insight on the disease and desire for care ...).

Detailed Description

The investigators will recruit a total of 200 patients with an eating disorder in the university hospital of Montpellier.

Participation consists of a one-day visit with a multidisciplinary assessment. No action is specific to research. This is the usual management of patients with eating disorders addressed to our department.

Study Timeline

• Status Verified: 2019-09
• Study First Submitted: 2019-09-13
• Study First Submitted QC: 2019-09-13
• Study First Posted: 2019-09-16
• Study Start: 2019-10-01
• Primary Completion: 2019-12-01
• Study Completion: 2019-12-30
• Last Update Submitted: 2020-03-09
• Last Update Posted: 2020-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Level of functional impairment assessed by the clinician with the FAST scale	1 day	We aim to investigate the link between global functioning and decision making abnormalities of patients with eating disorder.; The Functioning Assessment Short Test (FAST) is composed of 24 items assessing various dimensions of daily functionning. Each item is ranged from 0 (no difficulty) to 3 (major difficulty) like a likert scale. The FAST is subdivided in 6 subscales : Autonomy (from 0 to 12), Professional activity (from 0 to 15), Cognitive functioning (from 0 to 15), Finances (from 0 to 6), interpersonal relationships (from 0 to 18) and Hobbies (from 0 to 6). The total score is the sum of the 6 subscales from 0 to 72. A hight score reveal hight difficulties in daily functionning

Secondary Outcome Measures

Name	Time	Method
Decision making assessed by the Iowa Gambling Task	1 day	We aim to investigate the link between decision making abnormalities and eating disorder caracteristicus
Level of central coherence assessed by the Rey Figure Test	1 day	We aim to investigate the link between central coherence abnormalities and eating disorder caracteristicus
Level of cognitive flexibility assessed by the Brixton test	1 day	We aim to investigate the link between cognitive flexibility abnormalities and eating disorder caracteristicus

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France