ACTRN12605000675628招募中4 期
A cross-over study to evaluate the effects of a cognitive behavioural therapy (CBT) intervention, followed by a randomised trial of sertraline/placebo (for non-responders to CBT only) in the treatment of comorbid depression and substance misuse to improve outcome in depression and substance use levels.
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 16 Years 至 26 Years（—）
- 性别
- All
入选标准
- •All patients with acute major depressive episode (more than one month) and concurrent DSM-IV substance abuse/dependence or the use of any illicit drug on a weekly basis in the month prior to referral, or alcohol consumption exceeding NHMRC guidelines Patients must speak English as their preferred language, and have an estimated IQ >80.
排除标准
- •Current or past history of psychosis, significant head injury, seizures, neurological disease, impaired thyroid function, and steroid use; history or current evidence of any other significant clinical condition; participation in any other studies involving investigational or marketed products, concomitantly or within 30 days prior to entry in the study; treatment with an antidepressant within past 30 days; pregnant or lactating women, or women of childbearing potential not using an acceptable method of contraception.
研究者
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