Validation of an image based measurement method for the head circumference as an alternative method for diagnosing micro- or macrocephaly

• Conditions: Q02; Q75.3; Macrocephaly; Microcephaly

• Registration Number: DRKS00021808
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-26
• Study Completion: 2021-06-01
• Results First Posted: 2021-12-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

Pediatric patients in whom a 3D T1 sequence has been acquired as part of an MRI scan since January 1st 2010 and from whom a head circumference was measured clinically in a timely manner. A deviation of the clinically determined KU from the date of the imaging is permitted by +/- 3 months in children over 6 years of age, by +/- 1 month in children from 2 to 6 years of age and by +/- 1 week in children before the second year of life.

Exclusion Criteria

Incomplete imaging or no clinical measurement within the given timespan.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of the interrater reliability of the retrospective measurement of the head circumference using MRI imaging<br>

Secondary Outcome Measures

Name	Time	Method
Comparison with the clinically collected data<br>Correlation of the radiologically measured head circumference with the intracranial volume