A Pilot Randomized Cross-over Study of Two Mean Arterial Pressure Targets During and Immediately After Cardiac Surgery

Completed

• Conditions: cardiac surgery; Anaesthesiology - Anaesthetics; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system

• Registration Number: ACTRN12611001107910
• Lead Sponsor: Austin Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-10-24
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Open heart cardiac surgery
Ability to insert a hepatic venin cannula
Informed consent

Exclusion Criteria

Inability to insert hepatic vein catheter
Emergency surgery
Severe disorder of coagulation
Lack of informed consent
Jeovah's witness
Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hepatic vein oxygen saturation.<br>This is measured by the insertion of curved catehter from the femoral vein guided by X-ray into the hepatic vein.<br>The catheter can be used to obtain blood form the hepatic vein which is the then taken to a blood gas machine, where arterial blood gases and oxygen saturation can be measured.[each 2 hours of intervention]

Secondary Outcome Measures

Name	Time	Method
evel of cytokines.<br><br>The blood levels of interleukin 6, interleukin-10 and tumour necrosis factor will be measured by ELISA techniques in blood obtained form the radial artery cannula and from the hepatic vein cannula.[each 2 hours of intervention]