ACTRN12608000449336已完成2 期
A Randomised Phase II/III Trial to evaluate the efficacy and safety of Weekly Cisplatin Chemoradiotherapy +/- low-dose celecoxib for locoregional nasopharyngeal carcinoma
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 15 Years 至 80 Years(—)
- 性别
- All
入选标准
- •1. Pathologically proven locoregional nasopharyngeal carcinoma.
- •2. No prior therapy
- •3. No clinical or imaging evidence of distant metastasis at the time of study enrollment
- •4. Karnofsky performance status = 70
- •5. Written informed consent
- •6. Normal or acceptable liver, kidney and bone marrow function
排除标准
- •1. Prior therapy
- •2. Clinical or imaging evidence of distant metastasis
- •3. Patients with a known contraindication (e.g. gastric ulcer) or allergy to COX-2 inhibitors
- •4. Patients with severe heart, cardiovascular, liver, renal, inflammatory intestinal or blood coagulation disorders,
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