The influence of propofol and inhalational anesthetics on postoperative pain perception - QST and anesthetics

ZARI - Univeristätsmedizin Göttingen0 sites60 target enrollmentApril 22, 2010

Overview

No summary available.

Registry

who.int

Start Date

April 22, 2010

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional clinical trial of medicinal product

Sex

All

Sponsor

ZARI - Univeristätsmedizin Göttingen

•1\.Written informed consent obtained prior to study entry including informed consent for genetic research
•2\.Both genders (male and female)
•3\.Healthy adults aged \=18 to \< 65 years
•4\.Body weight 50 – 100 kg and BMI 18 – 28 kg/m²
•5\.Willingness to meet the study instructions and to co\-operate with the study personell.
•6\.Female subjects will only be included if they have negative serum pregnancy test immediately before the general anesthesia.
•7\. Patients with ASA I or II classification who undergo elective surgery with planned surgical time of up to 150 minutes and minimal to moderate surgical trauma.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1\.2 Adults (18\-64 years) yes

•1\.Involvement in the planning and conduct of the study (applies to staff directly employed at the study site / department)
•2\.Participation in a clinical study during the last 30 days or use of any other investigational or non\-registered drug or vaccine during the study period or within 30 days preceding the first dose of study drugs
•3\.Age \< 18 years or \> 65 years
•4\.Any relevant clinical pathological which might affect the study measurements or pharmacokinetics or pharmacodynamics of the tested substances.
•5\.Any disease affecting central or peripheral nerve system.
•6\.Any disease in which use of the investigational medicinal products might be contraindicated.
•7\.Any acute inflammatory disease