A randomised clinical trial evaluating the effect of remifentanil vs fentanyl during cardiac surgery on the incidence of chronic thoracic pain.

Phase 4

Completed

• Conditions: chronische thoracale pijn; chronic thoracic pain; chronic pain on chest

• Registration Number: NL-OMON41643
• Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 126

Inclusion Criteria

All patients living in Utrecht and surroundings undergoing cardiac surgery via sternotomy, including a CABG and/or valve replacement, admitted to the ICU or PACU in the St. Antonius hospital, between 18 and 85 years old, weighing between 45 and 140 kg, written informed consent.

Exclusion Criteria

- Pregnancy/ breastfeeding
- Language barrier
- History of drug abuse
- Neurologic condition such as peripheral neuropathy
- Known morphine or paracetamol allergy
- BMI groter dan 35 kg/m2
-Prior cardiac surgery (sternotomy)
-Chronic pain conditions

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoints:<br /><br>- The percentage of patients reporting chronic thoracic pain one year after<br /><br>cardiac surgery. </p><br>