Effect of Position During Spinal Anesthesia on Hemodynamic Change in Pregnant Women Undergoing Cesarean Section: Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 140
- 试验地点
- 2
- 主要终点
- Hypotension
研究概览
简要总结
Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic. For right lateral decubitus, the enlarged uterus compresses inferior vena cava that may decrease venous return and cardiac output. This leads to hypotension.The hypothesis is the right lateral position during spinal anesthesia in pregnant women will be had hemodynamic changing more than the left lateral position. This objective is to compare hemodynamic change between left and right lateral position during spinal anesthesia in pregnant women undergoing cesarean section.
详细描述
Study design: A randomized controlled trial
Study setting:
The study will be conducted in the operating rooms at Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand
Study period:
The total duration of participation in the randomized study is up to the operative day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Signed informed consent
- •Term pregnancy
- •Spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml
排除标准
- •Contraindication for spinal anesthesia
- •Height < 150 cm.
- •Complicated pregnancy e.g. heart disease, preclampsia, eclampsia, diabetes millitus, twin, abrupt placenta, placenta pre via, and fetal distress
- •Failed spinal anesthesia
研究组 & 干预措施
Right lateral decubitus position
Right lateral decubitus position during spinal anesthesia
干预措施: Right (Procedure)
Left lateral decubitus position
Left lateral decubitus position during spinal anesthesia
干预措施: Left (Procedure)
结局指标
主要结局
Hypotension
时间窗: after bupivacaine injection until 15 minutes after spinal anesthesia
Systolic blood pressure lower than 90 mmHg or decrease more than 20% of baseline
次要结局
- Apgar score at first minute and fifth minute(Child delivery at first minute and fifth minute)
- Ephedrine consumption(intraoperative)
研究者
Panthila Rujirojindakul
Dr
Prince of Songkla University