Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition Patients

Completed

• Conditions: Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition

• Registration Number: NCT04954755
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

This study intends to strengthen the discussion on the risk factors of RFS in critically ill patients, and construct an RFS risk prediction model which is easy for clinical medical staff to use and has a high sensitivity and specificity; In order to help medical staff to identify the high-risk groups of RFS in critically ill patients efficiently and accurately, and take targeted care and treatment for patients, so as to reduce the adverse consequences of RFS on critically ill patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-01
• Primary Completion: 2020-10-31
• Study Completion: 2020-10-31
• Status Verified: 2021-06
• Study First Submitted: 2021-07-06
• Study First Submitted QC: 2021-07-07
• Last Update Submitted: 2021-07-07
• Study First Posted: 2021-07-08
• Last Update Posted: 2021-07-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 553

Inclusion Criteria

• (1) Age ≥18 years old; (2) Patients with mechanical ventilation; (3) First admission to ICU； (4) The time of receiving enteral nutrition support in ICU was ≥ 3 days.

Exclusion Criteria

• (1)Ppregnant women or lactating patients;(2) Patients with incomplete information;(3) There are other risk factors leading to hypophosphatemia, such as continuous hemodialysis , hyperphosphatemia treatment,Parathyroid gland resection was performed within 3 months.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of RFS	from December 1, 2019 to October 31, 2020	Occurrence of RFS：Within 72 hours after feeding serum phosphorus \< 0.0.87mmol/L, or from the baseline levels drop \> 0.16% or drop \> 30%;And (or) hypokalemia, hypomagnesemia, hypocalcemia and corresponding clinical symptoms.

Trial Locations

Locations (1)

Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition; 🇨🇳 Hanzhou, Zhejiang, China