Clinical outcomes of head and neck cancers comprehensively treated with radical intent at HBCHRC Vishakhapatnam- A Retrospective Analysis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 600
- Locations
- 1
- Primary Endpoint
- To assess clinico-epidemiological profile and outcomes of head and neck cancer patients comprehensively treated with radical intent at HBCHRC Vishakhapatnam
Study Overview
Brief Summary
Head and neck cancers (HNC) are a heterogeneous group of cancers involving mucosal surfaces of the lip, tongue, oral cavity or mouth, oropharynx, nasopharynx, hypopharynx, pharynx not otherwise specified and larynx. Head and neck squamous cell carcinoma (HNSCC) accounts for more than 0.9 million cases and 0.4 million deaths worldwide.In India, there are more than 0.22 million cases and 0.12 million deaths according to the GLOBOCAN, 2020. Cancers of the lip and oral cavity are the second most common cancers following breast cancer. HNC constitutes 10.4% of the cancer burden and they account for 16.1% of cases in males and 4.8% of the cases in females. Information on cancer patterns and survival is essential for effective planning of cancer control interventions. Hence, we aimed at studying the clinico-epidemiological profile of HNC patients admitted in hospital from 2021 to 2023 and also to estimate the survival rate in them.
This is a retrospective study with duration of 1 year and recruiting all the patients treated between 1st January, 2021 and 31st December, 2023 at Homi Bhabha Cancer Hospital and Research Centre, Visakhapatnam. Head and neck cancer patients who were treated comprehensively (received entire treatment in HBCH&RC) with radical intent will be included in our study. Outcomes will be measured as: Overall survival, Disease free survival, locoregional control, Pattern of care and Patterns of failure.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 12.00 Year(s) to 90.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •All head and neck cancer patient comprehensively (received entire treatment in HBCH&RC) treated with radical intent at HBCH&RC.
Exclusion Criteria
- •Received at least one radical intent of treatment outside HBCH&RC
- •Treated with palliative intent.
Outcomes
Primary Outcomes
To assess clinico-epidemiological profile and outcomes of head and neck cancer patients comprehensively treated with radical intent at HBCHRC Vishakhapatnam
Time Frame: 2 years
Secondary Outcomes
- To assess the locoregional control (LRC)(2years)
- To assess disease free survival (DFS)(2years)
- To assess Overall survival (OS)(2years)
- To assess p16 positivity by IHC(2years)
- To assess acute & late toxicities(2years)
- To find out prognostic factors associated with LRC, DFS & OS(2years)
Investigators
Dr Umesh Mahantshetty
Homi Bhabha Cancer Hospital and Research Center