NCT00264017已完成不适用
Palladium-103 Seed Implant and Single Daily Dosing of Uroxatral Vs Twice Daily Dosing of Flomax-A 3 Month Retrospective Efficacy Analysis
Dattoli Cancer Center and Brachytherapy Research Institute1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2005年11月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
In the past ten years, newer drugs with more selective affinity for the alpha-receptor have been introduced. Alfuzosin (Uroxatral) and Tamulosin(Flomax are two second generation alpha-blockers. In the course of our clinical proctice, both drugs have been used routinely. This retrospective comparison is intended to be a priliminary comparison of their effectiveness and side effects.
研究设计
- 研究类型
- Observational
- 观察模型
- Defined Population
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 45 Years 至 80 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Males age 45-80 years
- •Diagnosis of prostate cancer
- •Status post IMRT and Palladium-103 seed implantation and initiated alpha blocker therapy with alfuzosin10mg daily or tamulosin 0.4mg bid at time of seed implantation
- •Baseline AUA score< or =12
- •May be on antiandrogenand/or alpha reductase therapy
- •Patients receiving IMRT followed by Palladium-103 Brachytherapy implantation as the primary therapy for prostate cancer with curatives intent -
排除标准
- •History of insulin-dependent diabetes
- •Uncontrolled hypertention
- •History of symptomtic hypotension (including syncope and dizziness)
- •Pre-existing obstructive uropathy based on history of BPH and or Acute Urinary Retention
- •Pre-existing prostatitis either continuous or intermittent
- •Concurrent use of any other anticholinergics
- •previous or concurrent usage of LHRH agonist
研究者
研究点 (1)
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