COMPARATIVE CLINICAL STUDY OF GOMUTRA HARITAKI AND NAVAK GUGGULU IN MEDOROGA (DYSLIPIDEMIA)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Improvement in Lipid Profile Parameters ( Total Cholesterol, LDL,HDL,Triglyceride, VLDL)
研究概览
简要总结
Comparative Clinical Study of Gomutra Haritaki and Navak Guggulu in Medoroga (Dyslipidemia)
Scholar: Mamta
Institution: Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan, under Uttarakhand Ayurved University
Department: Kayachikitsa
Study Period: 18 months
Sample Size: 60 patients
Summary:
This clinical study investigates the comparative efficacy of two Ayurvedic formulations—Gomutra Haritaki and Navak Guggulu—in the management of Medoroga, which is correlated with dyslipidemia in modern medicine. Medoroga, as described in Ayurveda, results from sedentary lifestyle and improper dietary habits leading to the accumulation of Meda (fat), and manifests with symptoms like heaviness, breathlessness, excessive thirst, and lethargy.
Due to the side effects and limitations of modern hypolipidemic drugs, the study explores the potential of Ayurvedic alternatives that are cost-effective, safe, and holistic. Gomutra Haritaki is known for its Amapachana and Agnideepana effects, whereas Navak Guggulu has Lekhana, Medohara, and Srotoshodhana properties.
A randomized, open-label, two-arm clinical trial is planned, with 30 patients in each group. Patients will be treated for 60 days and assessed using both modern (lipid profile, BMI, body weight) and Ayurvedic parameters (subjective symptoms of Medoroga). Results will be statistically analyzed to evaluate and compare the efficacy of both drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients diagnosed with Medoroga (Dyslipidemia) based on lipid profile criteria Age 20 to 70 years of either gender Patients with BMI mpre than 25 kg per m² Patients willing to participate in the study.
排除标准
- •Patients with past history of myocardial infarction (MI), unstable angina, or stroke Patients with AIDS, cancer, tuberculosis, uncontrolled diabetes mellitus, psychiatric illness, or uncontrolled hypertension Pregnant and lactating women.
结局指标
主要结局
Improvement in Lipid Profile Parameters ( Total Cholesterol, LDL,HDL,Triglyceride, VLDL)
时间窗: Baseline,30 days and 60 days
次要结局
- Reduction in symptoms such as breathlessness, excessive thirst, excessive hunger, excessive sweating, and lethargy(Baseline,30 days and 60 days)
研究者
Mamta
Patanjali Bhartiya ayurvigyan evam anusandhan sansthan Haridwar Uttarakhand