NCT00041379Unknown1 期
Phase I/II Study to Assess the Safety and Efficacy of Low Doses of Beta LT in Patients With Waldenstrom's Macroglobulinemia
适应症
相关药物
试验速览
- 阶段
- 1 期
- 试验地点
- 2
研究概览
简要总结
RATIONALE: Biological therapies such as beta alethine use different ways to stimulate the immune system and stop cancer cells from growing.
PURPOSE: Phase I/II trial to study the effectiveness of beta alethine in treating patients who have Waldenstrom's macroglobulinemia.
详细描述
OBJECTIVES:
- Determine the antitumor effects of low-dose beta alethine in patients with Waldenstrom's macroglobulinemia.
- Determine the effects of this drug on anemia, performance status, and disease symptoms in these patients.
- Determine the effects of this drug on the immune system of these patients.
- Determine the safety of this drug in these patients.
OUTLINE: This is a multicenter study.
Patients receive beta alethine subcutaneously on days 1, 15, 29, 43, 57, and 71. Courses repeat every 85 days in the absence of disease progression or unacceptable toxicity.
Patients are followed for 30 days.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
1 期
Beta Alethine in Treating Patients With MyelomaMultiple Myeloma and Plasma Cell NeoplasmPrecancerous ConditionNCT00006466LifeTime Pharmaceuticals
Unknown
1 期
Beta Alethine in Treating Patients With Low-Grade LymphomaLymphomaNCT00007839LifeTime Pharmaceuticals
已完成
2 期
A Study on the Immune Response and Safety of a Combined Measles, Mumps, Rubella, Chickenpox Vaccine Compared to a Marketed Combined Vaccine, Given to Healthy Children 4 to 6 Years of AgeNCT05630846GlaxoSmithKline801
已完成
1 期
Safety and Immunogenicity Study of tgAAC09, a Gag-PR-RT AAV HIV VaccineHIV InfectionNCT00482027International AIDS Vaccine Initiative80
已完成
1 期
Cellular Adoptive Immunotherapy in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal CancerPeritoneal Cavity CancerOvarian CancerNCT00101257Fred Hutchinson Cancer Center18