The Impact of Lumboscopy Versus Laparoscopy on Ventilatory Mechanics

Not yet recruiting

• Conditions: Anesthesia; Mechanical Ventilation; Respiratory Physiology

• Registration Number: NCT06776068
• Lead Sponsor: University of Chile

Brief Summary

There are several techniques for performing minimally invasive urological surgeries. Among them, laparoscopic surgery, robotic surgery, and lumboscopy are noteworthy (1). The medical literature extensively documents the impact of pneumoperitoneum a procedure involving the insufflation of the peritoneal cavity with carbon dioxide (CO2), which is essential for laparoscopic and robotic surgeries on ventilatory mechanics.

As an alternative, CO2 insufflation into the retroperitoneum, as utilized in lumboscopic surgery, has been proposed. This approach is believed to exert a lesser impact on respiratory function and pulmonary mechanics. However, it is important to note that no conclusive evidence has yet been found to support this claim.

Assessing the impact of lumboscopic surgery could help establish it as a viable alternative for patients with pulmonary conditions, where mechanical ventilation poses significant challenges. To explore this possibility, a physiological study was designed to compare the effects of laparoscopic and lumboscopic surgery on ventilatory mechanics.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-12
• Study First Submitted: 2025-01-09
• Study First Submitted QC: 2025-01-09
• Last Update Submitted: 2025-01-09
• Study First Posted: 2025-01-15
• Last Update Posted: 2025-01-15
• Study Start: 2025-02-01
• Primary Completion: 2025-03-01
• Study Completion: 2026-03-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age >18 years old
• ASA PS II-III
• Elective surgery
• Surgery: Partial or total nephrectomy

Exclusion Criteria

• Severe pulmonary pathology
• Severe cardiovascular pathology
• Open surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Parameters of ventilatory mechanics	intraoperative	Static compliance Plateau pressure Driving pressure Transpulmonary pressure

Trial Locations

Locations (2)

Hospital Clínico Universidad de CHile; 🇨🇱 Santiago, Chile

Instituto Nacional del Cáncer; 🇨🇱 Santiago, Chile